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تقریظ دوم

تقریظ ِ دوئم
زیرِ نظر کتاب’’نسیم سخن‘‘ نظروں سے گزری ۔یہ ایک مجموعہ تقریر ہے اور خدمتِ خلق کے جذبہ کے تحت اس کو مدون کیا گیا ہے۔ اس میں طلبا و طالبات کی ضروریات کو خصوصی طور پر پیشِ نظر رکھا گیا ہے۔ طلبا کے لیے ترغیبی انداز اختیار کیا گیا ہے۔ تقاریر میں اختصار اور جامعیت کو ملحوظِ خاطر رکھا گیا ہے۔ گزشتہ ادوار میں مقابلہ جات میں متعدد مرتبہ پوزیشنیں حاصل کرنے والا حافظ محمد اکرم راشدؔ کا یہ مجموعہ تقاریر ’’نسیم سخن‘‘ آئندہ بھی ضرور کفایت کرے گا۔ اس میں موجود مواد تشنگانِ علم کی پیاس بجھانے میں ممد و معاون ثابت ہو گا۔ ایک جگہ پر اتنی تقاریر کا مل جانا ناممکن نہیں تو محال ضرور ہے۔
حافظ محمد اکرم راشدؔ سے میرا دیرینہ تعلق ہے۔ یہ ایک علم دوست انسان ہیں۔ خاندانی شرافت اور علم کی بہاریں انھیں ورثے میں ملی ہیں۔ان کی طبع میں حلم و بردباری ہے۔ اپنی تمام تر خصوصیات کو عوام الناس میں بالعموم اور طلبا میں بالخصوص منتقل کرنے کا جذبہ رکھتے ہیں۔ یہ دینی علوم کا حظِ وافر رکھنے کے ساتھ ساتھ ایم۔اے، ایم۔ایڈ بھی ہیں اور ایم۔اے عربی میں گولڈ میڈلسٹ بھی ہیں۔آپ ایک گورنمنٹ ہائی سکول سے بطور رئیس مدرسہ ریٹائر ہوئے ہیں۔ فی الوقت جامع مسجد این۔ بلاک عارف والا میں بطور خطیب فرائض سر انجام دے رہے ہیں۔ عارف والا اوراس کے مضافات میں بطور خوش نویس بھی ان کی شناخت ہے۔قبل از ایں ’’نگارشاتِ راشد‘‘ کے نام سے مختلف مضامین و مقالات پر مشتمل ان کی کتاب زیورِ طباعت سے آراستہ ہو کر منظرِ عام پر آچکی ہے۔اللہ تعالیٰ ان کی اس کد وکاوش کو قبول فرمائے۔
رانا کوثر خاں
چیف ایکزیکٹو آفیسر(ایجوکیشن)
ڈسٹرکٹ ایجوکیشن اتھارٹی ، پاک پتن

قرآن و حدیث کی روشنی میں تعمیر کردار و شخصیت اور نصاب اسلامیات: ایک تنقیدی مطالعہ

Islam gives the idea of collective life and tries for human development. The basic idea of the teaching of Islam is that the individual must be true and active worker of society. He must have moral values and principles clearly. In addition, he tries constantly that a Muslim should perform saying of Allah and human rights properly. In this way, Islam tries to work on the behavior, morality, and habits of people and tries his best to properly enhance the different aspects of personality.  For this, the life of Prophet Muhammad? Is a complete code of life. The good characteristics of Muslims are considered praiseworthy that are truth, brotherhood, justice, forgiveness, the oneness of Allah and keepings. In the same way, the things which are condemned by Islam are bride, misery, theft, backbiting, telling lies, blaming others, self-centeredness, close vision, dishonesty, garrulous, greediness, showiness manners, jealousy,  un-obligation, clashes, hatred and etc. The philosophy of character building and personality development in Islam is the Muslims should avoid all bad works and develops good qualities in him as discussed before so that a Muslim should be a very useful and pious citizen of society. And we all know that education especially we can say that Islamic Education is a tool of change. So education is worthless if it does not create change in the minds of people and society. It is useless if it does not build the moral character regarding the personality development of the students. Islam tells us all about the values which are fruitful for humanity and are beneficial to human beings. For this purpose, it is necessary that we should give awareness of Islamic values to the people through Islamic education. It is only possible if the textbooks are designed according to the Islamic concept and values as well as teachers and parents play their effective role in the development of the personality of their children. Pakistan is a Muslim country and has its own religious, moral, political and social values and being a Muslim through an effective Islamic educational system, we can transfer these values to our new generation. Our curriculum is playing key role in the personality development and character building of the students or not is the main question so that this article is being written. In this article keeping in view the aims and objectives of the curriculum of Islamic Studies and following the Quranic verses and Hadith, we will try to analyze whether it is building the personality or character of students or not. After that, the conclusion and recommendations will be given keeping in view the analysis.

New Tetrazolopyridine-Acetohydrazide, Bis-3- Phenylamino -5-Pyridinyl-Oxadiazolethione and Thiazolocoumarin Derivatives: Synthesis and Characterization

In the present endeavor the aetohydrazide derivatives and diacylhydrazine derivatives were synthesized and characterized. The key intermediate 2-(5-(pyridin-3/4-yl)-2H-tetrazol-2-yl)acetohydrazide was reacted with substituted-benzaldehydes and acid chlorides to give two classes of compounds: (i) N΄-(Substituted-benzylidene)-2-(5-(pyridin-3/4-yl)-2H-tetrazol-2-yl) acetohydrazides (ii) Substituted-N΄-(2-(5-(pyridin-3/4-yl)-2H-tetrazol-2-yl)acetyl)benzohydrazides The acetohydrazides were screened for their in vivo antidiabetic activity and most of the derivatives have effective role in lowering plasma glucose, exerting potential of being good antidiabetic agents. Tetrazolo-pyridine-diacylhydrazines were tested for their inhibitory activity against nucleotide pyrophosphatase (hNPP1 & hNPP3) and the results show that NPP1 and NPP3 reveal differential susceptibility to benzohydrazide inhibitors. Some of the newly-synthesized analogues are selective inhibitors of NPP1 while some others selectively retard the activity of NPP3. The derivatives with IC50 values lesser than or closer to Suramin, (standard used) may have potential application in the treatment of neurodegenerative, cancer and metastatic diseases. In addition, Mannich bases act as important biologically-active compounds with high medicinal value, therefore a series of bis Mannich bases type derivatives were synthesized and characterized. Benzidine, 5-(pyridin-4-yl)-1,3,4-oxadiazole-2(3H)-thione and substitutedbenzaldehydes were reacted in 1:2:2 molar ratio giving 3,3΄-(4,4΄{[1,1-Biphenyl)-4,4΄-diylbis(azanediyl)]bis(substitutedphenyl)methylene)]bis(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-4,2-diyl)}bis(4-pyridine) by means of simple and easy procedure. Coumarin and thiazole derivatives are well-known for their wide range of fluorescent and medicinal applications. Some new series of 3-thiazolyl-coumarins were designed containing both these important nuclei in a single structural unit, synthesized and characterized. The intermediate 3-(2-Bromoacetyl)-2H-chromen-2-one led to two different series of 3-thiazolylcoumarins: (i) 3-(2-(Substituted phenylamino)thiazol-4-yl)-2H-chromen-2-ones (ii) (ii) 3(2-(2-(Substitutedbenzylidene)hydrazinyl)thiazol-4-yl-2H-chromen-2-ones The second series was tested against acetylcholinesterase and butyrylcholinesterase and their structure–activity relationship was established. Studies tagged them as the potential inhibitors of cholinesterase (acetylcholinesterase and butyrylcholinesterase). The docking studies showed that these synthesized compounds possess better interaction patterns with butyrylcholinesterase over acetylcholinesterase. The main objective of the present investigation was to develop new potent and selective compounds, which might be further optimized to prevent the progression of the Alzheimer’s disease
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