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ڈاکٹر محمد ایوب قادری

ڈاکٹر محمد ایوب قادری
پاکستان وبھارت کے علمی اور دینی حلقوں میں یہ خبر بڑے رنج وغم کے ساتھ سنی گئی کہ۲۵/نومبر۱۹۸۳ء کوپاکستان کے ایک نامور ادیب،مصنف اور مؤرخ ڈاکٹر محمد ایوب قادری کراچی میں ٹریفک کے ایک حادثے میں جاں بحق ہوگئے۔ وفات کے وقت ان کی عمر۵۶برس کے لگ بھگ تھی۔
قادری صاحب روہیلکھنڈ کے مشہور تاریخی قصبے آنولہ کے رہنے والے تھے۔ان کی ابتدائی تعلیم بدایوں اوربریلی میں ہوئی۔تقسیم ملک کے بعد موصوف کراچی چلے گئے۔کراچی جاکر انھوں نے اپنی تعلیم جاری رکھی اوربالآخر اردو کالج کراچی میں شعبۂ اردو میں لیکچرار مقرر ہوئے اور محنت،لگن اورخلوص کی بدولت آخر میں شعبۂ اردو کے صدر بن گئے۔
قادری صاحب کوروہیلکھنڈ کی تاریخ، رجال اور اماکن پربڑی دسترس تھی۔اس کے علاوہ۱۸۵۷ء کی جنگِ آزادی کے ہیرو ان کی تحقیق کا محور تھے۔ انھوں نے مخدوم جہانیاںؒ کاایک تذکرہ لکھا اورمآثرالامراء کااردو میں ترجمہ کیا۔ مرحوم نے مجلہ اردو کالج کراچی کے کئی شاندار نمبرنکالے۔پاکستان اوربھارت کے علمی وادبی رسائل میں ان کے مضامین اکثرچھپتے رہتے تھے۔
۲۵/نومبر کی شام کو موصوف اپنے گھرواقع شمالی ناظم آباد سے چلے۔ابھی انھوں نے بمشکل سو سواسوگز کا فاصلہ طے کیاہوگا کہ ایک ویگن ان کے سرسے ٹکرا گئی اورموصوف موقع پرہی جان بحق ہوگئے۔
یہ بھی عجیب بات ہے کہ ان کے ایک حقیقی بھائی ابومعاویہ نعمت اﷲ قادری بھی ۲/فروری۱۹۸۱ء کولیاقت آباد کراچی میں ٹریفک کے ایک ایسے ہی حادثے میں جاں بحق ہوئے تھے۔ابومعاویہ کودیکھ کرقرنِ اوّل کے مسلمانوں کی یادتازہ ہوتی تھی۔انھوں نے اس مادی دور میں اپنے تمام بچوں کودینی مدارس میں تعلیم دلوائی۔
یہ دونوں بھائی بڑی خوبیوں کے مالک اور اعلیٰ انسانی اوصاف سے متصف تھے۔اﷲ تعالیٰ ان کومغفرت وبخشش کی نعمتوں سے سرفراز فرمائے۔
[مارچ۱۹۸۴ء]

 

The Impact of Lane Discipline on Speed and Time Headway

Lane discipline has a major impact on traffic density, speed, and time headway. In this paper, three-dimensional (3D) centre lane marking is used to enforced lane discipline.  Traffic congestion mitigated with three dimensional lane marking as the speed and headway increased. The Camlytics is used to observed the egress and ingress time. The statistics analysis noticed an increase in speed and headway after 3D lane marking. Gamma and Lognormal distributions are found the best fit for speed before and after 3D marking, respectively. Normal and Weibull distributions are the best fit for headway in the absence and presence of 3D lane markings, respectively. These distributions can be used for traffic flow characterization. This study recommends strictly enforcement of lane discipline to counter traffic congestion. 

Phytochemical and Pharmacological Investigations of Quercus Incana

The present study was aimed to extract, fractionate, isolate and standardize the chemical constituents from the plant, Quercus incana, in order to find out their phytochemical and pharmacological mode of action, so as to discover a new source for potentially active constituents used for the benefits of mankind. Quercus incana, which is a large evergreen tree belongs to family Fagaceae. The Fagaceae is a large plant family found in Asia, North America and Europe. Quercus incana has been used in different ailments such as diarrhea, neurosis, pyrexia, dysentery, pain, inflammation and burns healing in conventional medicines. It is also employed to treat gonorrhea and used as an astringent, diuretic, and various nervous disorders all over the world including Pakistan. In the present research work, the plant Quercus incana was explored for its chemical constituents using chromatographic and spectroscopic techniques for potentially new and therapeutically active agents. The bark portion was selected for isolation, on the basis of preliminary pharmacological activities and its common use by the local people and Hakims and Tabibs in different ailments. Some activities were performed on fruit extract also. Crude extract of bark and fruit of Quercus incana and the new compound isolated from bark were screened for various in-vitro and in-vivo biological activities like antibacterial, anti oxidant, analgesic, anti-inflammatory etc, inorder to give scientific background to various ethnomedicinal applications of the plant which will lead to safe, therapeutic, effective and economical way of treatment of different diseases and to examine and analyze the chemical composition of the plant. For the isolation of pure secondary metabolites, the ethyl acetate fraction (obtained from crude methanolic extract of the bark) was subjected to column chromatography. The structures of purified compounds were elucidated by using various sophisticated spectroscopic techniques i.e, 1H-NMR, 13C-NMR, COSY, NOESY, DEPT, HSQC, HMBC, UV, IR and EI-MS. The plant was found to be a new source of six compounds such as, betulinic acid, 9-octadecanoic acid methyl ester(z-form), gallic acid, gallic ester, b-sitosterol glucoside, and quercitin. Three known compounds like β-sitosterol, ursolic acid, and lupeol were also isolated. Quercuschin, which was a completely new compound was discovered for the first time from this plant source. Results of in-vivo biological studies reveal that the plant possesses very good property of producing peripheral and central analgesia. The data obtained from different experiments supports the use of the plant in relieving fever, and treating inflammatory conditions. The different in-vitro activities of new compound were conclusive of the fact that the plant is a good natural antioxidant and can be used to treat various bacterial and fungal infections. The isolation work done on the plant (bark) of Quercus incana yielded 10 compounds. In these 10 compounds, 7 were reported for first time from this plant species : THESE WERE , betulinic acid, 9-octadecenoic acid methyl ester(z-form), gallic acid, gallic ester, b-sitosterol glucoside,quercitin , and one compound NAMELY Quercuschin: was absolutely new and was never reported before from any source AND was discovered for the first time from this plant source. 3 compounds were KNOWN compounds: NAMELY β-sitosterol, ursolic acid, and lupeol, Findings of this research project, especially the biological activities of chemical constituents of the plant, strongly support the folkloric uses of the plant and its applications in traditional treatment. The isolated compounds strengthen these activities. However, further comprehensive research work on the crude extract as well as on isolated compounds is needed to explore and identify lead compounds of clinical effectiveness for the development of new drugs in order to strengthen the field of drug discovery.
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